Revisión
The effect of probiotics on the serum lipid levels in non-obese healthy adults with hyperlipidemia: A systematic review and meta-analysis of randomized controlled trials
Kaiwen Sun, Zhenzhu Liu, Hongyan Wang
Número de descargas:
11740
Número de visitas:
6242
Citas:
2
Compártelo:
Introduction: probiotics might have a potential effect to manage serum lipid levels as nutraceuticals. Objective: this systematic review was conducted to explore whether probiotics have an efficient result in non-obese healthy adults with hyperlipidemia. Methods: PubMed, Embase, the Cochrane Central Register of Controlled Trials, and Web of Science were searched for randomized controlled trials (from their commencement to January 2021). This meta-analysis was performed by Review Manager 5.3 and STATA 15.1. Changes in serum lipid levels after the intervention were used to evaluate the effect of the probiotics, which were expressed as the weighted mean difference (WMD) with a 95 % confidence interval (CI). Results: a total of 16 studies, which could be regarded as 21 independent trials with 1429 participants, were included in this meta-analysis following our inclusion criteria. It could be observed that probiotics could significantly lower total cholesterol (TC) (WMD: -0.34 mmol/L, 95 % CI: -0.45 to -0.23 mmol/L; p < 0.001, I2 = 73.9 %) and low-density lipoprotein cholesterol (LDL-C) (WMD: -0.26 mmol/L, 95 % CI: -0.36 to -0.17 mmol/L; p < 0.001, I2 = 79.0 %) levels in non-obese healthy adults with hyperlipidemia, while no significant effect between the probiotic intervention and control groups was observed on high-density lipoprotein cholesterol (HDL-C) (WMD: 0.00 mmol/L, 95 % CI: -0.02 to 0.02 mmol/L; p = 0.001, I2 = 56.6 %) and triglyceride (TG) (WMD: -0.08 mmol/L, 95 % CI: -0.18 to 0.01 mmol/L; p = 0.003, I2 = 52.4 %) levels. Conclusion: this systematic review showed that probiotics may provide a promising way to reduce serum lipid levels in non-obese healthy adults with hyperlipidemia, but their specific effect still needs more clinical experiments to be proven.
Palabras Clave: Hyperlipidemia. Non-obese healthy adult. Probiotics. Serum lipids.
Artículos Relacionados:
Artículo Especial: Aspectos dietoterapéuticos en situaciones especiales del paciente oncológico. prebióticos y probióticos, ¿tienen cabida en la terapia nutricional del paciente oncológico?
Mª José Sendrós Madroño
Artículo Especial: The association between water intake, body composition and cardiometabolic factors among children - the cuenca study
Marta Milla-tobarra , Antonio García-hermoso , Noelia Lahoz-garcía , Blanca Notario-pacheco , Lidia Lucas-de La Cruz , Diana P. Pozuelo-carrascosa , María José García-meseguer , Vicente Martínez-vizcaíno
Trabajo Original: Estudio del impacto del índice de masa corporal pretrasplante sobre el pronto funcionamiento del injerto renal
Rafael Fernandez Castillo , Gustavo R. Cañadas De La Fuente , Guillermo A. Cañadas De La Fuente , Emilia Inmaculada De La Fuente Solana , Rafael Jose Esteban De La Rosa , Juan Bravo Soto
Trabajo Original: Ingesta de proteína, lípidos séricos y fuerza muscular en ancianos
Norma Amador-licona , Evelin Valeria Moreno-vargas , Claudia Martinez-cordero
Trabajo Original: Papel de los prebióticos y los probióticos en la funcionalidad de la microbiota del paciente con nutrición enteral
María Dolores Ballesteros Pomar , Elena González Arnaiz
Trabajo Original: Dietary patterns, central obesity and serum lipids concentration in Mexican adults
Marisol Neri-Sánchez , Beatriz Elina Martínez-Carrillo , Roxana Valdés-Ramos , Alexandra Estela Soto-Piña , Joel Alberto Vargas-Hernández , Alejandra Donaji Benítez-Arciniega
Trabajo Original: Nutrición y microbiota en población pediátrica. Implicaciones sanitarias
Ana Isabel Jiménez-Ortega , Rosa María Martínez García , Marta Velasco Rodríguez-Belvis , Ana Belén Martínez Zazo , María Dolores Salas-González , Esther Cuadrado-Soto
Trabajo Original: Simbiosis en el tracto gastrointestinal humano
Francisco Guarner
Trabajo Original: Time-restricted feeding in dark phase of circadian cycle and/or westernized diet cause mixed hyperlipidemia in rats
Eryka Maria dos Santos Alves , Nathalia Caroline de Oliveira Melo , Ana Carolina Oliveira Costa , Humberto de Moura Barbosa , Nathália Cavalcanti de Morais Araújo , Gisélia de Santana Muniz , Elizabeth do Nascimento
Revisión: Revising concepts of artificial nutrition in contemporary surgery: from energy and nitrogen to immuno-metabolic support
Trabajo Original: A mixture of Lactobacillus plantarum CECT 7315 and CECT 7316 enhances systemic immunity in elderly subjects. A dose-response, double-blind, placebo-controlled, randomized pilot trial
Revisión: Evidence on the benefits of probiotics for preterm infants
Ana Maria Campos Martinez , Carmen Elizabeth Fernández Marín , Aida Ruiz López , Isabel Cubero Millán , José Uberos Fernández
Trabajo Original: Comparison of the biochemical, anthropometric and body composition variables between adolescents from 10 to 13 years old and their parents
Trabajo Original: Is there a relationship between oral hygiene and nutritional status in peritoneal dialysis patients?
Sonia López-Cisneros , Ailema González-Ortiz , Samuel Ramos-Acevedo , Ángeles Espinosa-Cuevas
Revisión: Effect of the use of probiotics in the treatment of children with atopic dermatitis; a literature review
Artículo Especial: Third Jesús Culebras Lecture - Molecular Biology and Clinical Nutrition; where do we stand and where do we go?
Artículo Especial: Probióticos en las enfermedades hepáticas
Artículo Especial: Aplicaciones clínicas del empleo de probióticos en pediatría
Revisión: Intestinal microbiota; relevance to obesity and modulation by prebiotics and probiotics
Revisión: Lactobacillus Paracasei subsp. Paracasei F19; a farmacogenomic and clinical update
Trabajo Original: Probióticos y enterocolitis necrotizante del prematuro; to NEC or not to NEC?, ésta es la pregunta
Trabajo Original: Effect of probiotics on human blood urea levels in patients with chronic renal failure
Trabajo Original: Nueva guía de práctica clínica sobre nutrición enteral del recién nacido de muy bajo peso al nacimiento; segunda parte
Trabajo Original: Predictors of hyperlipidemia during the first half of pregnancy in Mexican women
Trabajo Original: The effect of Saccharomyces boulardii in patients eligible for liver transplantation
Trabajo Original: Valoración del perfil lipídico y de la densidad mineral ósea en pacientes trasplantados renales
Revisión: Alimentación funcional para aliviar desórdenes gastrointestinales asociados a trastornos del espectro autista: Una revisión sistemática
Julián Herrera Mejía , Arnulfo Ramos-Jiménez , Florinda Jiménez Vega , Rocío Campos Vega , Aaron F. González Córdova , Abraham Wall-Medrano
Revisión: Effect of chia seed (Salvia hispanica L.) consumption on cardiovascular risk factors in humans: a systematic review
Revisión: Probiotics in the treatment of infantile colic: a meta-analysis of randomized controlled trials
YanPing Liu , Dejian Ma , XiYan Wang , YunZhi Fang
Revisión: Treating asthma patients with probiotics: a systematic review and meta-analysis
Qiwei Xie , Jiatian Yuan , Yaoweng Wang
Trabajo Original: Production of snack bar enriched with paraprobiotics grown in banana peel medium, nutritional, sensory and quality parameters
Merve Tokpunar , K. Esen Karaca Çelik , Murat Baş , Hakan Kuleaşan , Aylin Korkut Altıntaş
Trabajo Original: A randomized double-blind controlled clinical trial demonstrating efficacy of different probiotic strains on serum lipids and glycemic biomarker
Gözde Okburan , Murat Baş , Sultan Ogmen
Trabajo Original: Can consumption of traditional fermented foods protect against Hashimoto's thyroiditis?
Fatma Özgüç Çömlek , Muslu Kazım Körez
Trabajo Original: Effects of probiotic supplementation on blood lipids ın hypercholesterolemic obese patients: a randomized, double-blind, placebo-controlled pilot trial
Sibel Bulut , Seray Kabaran
Artículos más populares
Artículo Especial: VII Lección Jesús Culebras. Respuesta inflamatoria sistémica y disfunción/ fracaso multiorgánico tras una agresión: implicaciones metabólicas
Ante cualquier agresión, el organismo pone en marc...
Artículo Especial: VIII Lección Jesús Culebras. Medicina intensiva, nutrición e hiperglucemia: una relación muy estrecha
El paciente crítico presenta una respuesta metaból...
-
Licencia creative commons: Open Access bajo la licencia Creative Commons 4.0 CC BY-NC-SA
https://creativecommons.org/licenses/by-nc-sa/4.0/legalcode
