Número de descargas:
5783
Número de visitas:
2737
Citas:
0
Compártelo:
Background: trauma and severe infections cause remarkable metabolic changes in patient with SIRS from an adaptive response aimed to control the underlying disease, repairing damaged tissue, and to synthesize substrates. If the attack is intense and sustained and the patient has a compromised nutritional status, can evolve into multiple organ failure and death. Objective: assessment of nutritional proteic status and the involvement of proteins and inflammatory factors in critically ill patients. Method: multicenter observational analytical study in critical ill patients at the admission in ICU. Results and discussion: patients showed disturbances in clinical nutritional parameters which confirm their hypercatabolic situation, showing malnutrition state at admission, where 42.9% had plasma levels below the reference prealbumin. Amino acid profile was situated below the reference values and 99% of patients had low plasma transferrin. Significant differences were observed in total protein, ferritin and transferrin parameters adjusted by CRP levels, being higher when patients presented high inflammation in the case of ferritin and the opposite for the rest of parameters. Adjusting APACHE and SOFA scores according to low, medium and high severity, results showed significant differences in creatinine, urea, and transferrin, being lower at high severity grade for the last one. Conclusion: critical illness is characterized by a high degree of stress and accelerated degradation of proteins that cause malnutrition, systemic inflammation and organ dysfunction, with a significant association between albumin, ferritin and transferrin.
Palabras Clave: Critical patient. Hypercatabolism. Protein status. Amino acids. SIRS.
Licia De La Calle De La Rosa , Sara Bermejo De Las Heras , Antonio Blesa , Manuel Giner , Javier Arias Díaz
Sara Bermejo De Las Heras , Licia De La Calle De La Rosa , Javier Arias Díaz , Manuel Giner , Antonio Luis Blesa Malpica
Pilar Gomis Muñoz
María Andrea Aimar , Gabriela Pomiglio , Fernando Baccaro , Mario Traverso , Jorge Audisio , Priscila De Feo , Adriana Crivelli , Mariela Flores Lazdin
Dino Moretti , Melisa D. Ré , Nicolás S. Rocchetti , Daniel Horacio Bagilet , Claudio Jesus Settecase , Martín Buncuga , Marta Quaglino
Sergio Ruiz Santana
Ruth Lezama García , Luis Chel Guerrero , Juan José Acevedo-Fernández , David Betancur Ancona
Blanca G. Beltrán Piña , Martha I. González Castro , Marta Irene Gonzalez Castro
Maria Arrieta Loitegui , Pilar Gomis Muñoz , Cristian Rosas , Aitor Delmiro Magdalena , José Miguel Ferrari Piquero
Luis Serviá Goixart , Juan Carlos López Delgado , Teodoro Grau Carmona
Ángel Gil
Juan Carlos Montejo González , María Sánchez-Bayton Griffith , Lydia Orejón García
Pilar Gomis Muñoz , Maria Arrieta Loitegui , Cristian Rosas , Samantha Spiers , Martyn Shinn , Miguel Ángel Orbaneja
Isabela Bernasconi José , Vania Aparecida Leandro-Merhi , José Luis Braga de Aquino , José Alexandre Mendonça
Álvaro Huerta Ojeda , Andreina Domínguez de Hanna , Guillermo Barahona-Fuentes
Sheila Alejandra Campos León , Agustín Ramiro Urzua González , Manuel José Rivera Chávez , María de Lourdes Reyes Escogido , Jaime Rivera Morales , Rodolfo Guardado Mendoza
Fátima Martínez-Lozano Aranaga , María Jesús Gómez Ramos , Maria del Carmen Sánchez Álvarez
Juan Carlos Montejo González
María Luisa Bordejé , Mar Juan Díaz , Mónica Crespo , Mireia Ferreruela , Esther Solano
Iván Armando Osuna-Padilla , Nadia Carolina Rodríguez-Moguel , Adriana Aguilar-Vargas , Sebastián Rodríguez-Llamazares
José Gómez-López , Matías Monsalves-Álvarez
Erika Ibarra Pastrana , Aurora Elizabeth Serralde Zúñiga
María Luisa Bordejé , Clara Vaquerizo Alonso
Guillermo Barahona-Fuentes , Álvaro Huerta Ojeda , Sergio Galdames Maliqueo , María-Mercedes Yeomans-Cabrera , Carlos Jorquera Aguilera
Iván Armando Osuna-Padilla , Nadia Carolina Rodríguez-Moguel , Laurie Abril López-Orduña , Ana Lucía Gómez-Rodríguez , Alan García-Grimaldo , Sebastián Rodríguez-Llamazares , Ismael Maldonado-Beltrán , Martín Armando Ríos-Ayala , Carmen Margarita Hernández-Cárdenas
Sergio Ruiz Santana
Samara Palma Milla
M.ª Luz Montero González
Rosa M. Ortega , Ana Isabel Jiménez-Ortega , Rosa M. Martínez García , Adrián Cervera-Muñoz , María Dolores Salas-González
Jordi Parisi , Itziar Martínez de Lagran , Mateu Serra-Prat , María Roca Fontbona , Raquel Merino , M.ª Carmen de la Torre , Lluis Campins , Juan Carlos Yébenes
Pilar Lalueza Broto , Juan Carlos López Delgado
Juan Carlos Montejo González
Joaquín Álvarez Rodríguez
Eva María Menor Fernández
Ante cualquier agresión, el organismo pone en marc...
El paciente crítico presenta una respuesta metaból...